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While a systematic review showed that kava does not have negative effects on cognition (37) , there have been case reports of impairment consistent with CNS depressant effects, including slow, slurred speech and flaccid muscle tone (45)

Exp Neurol 304:102113

It should be noted that eryptotic RBCs are cleared from the circulation in an efferocytosis-dependent fashion within minutes, in contrast to senescent erythrocytes [77], which require days to be engulfed by macrophages and cleared [72]

[74] at the University of Auckland considering almost 20 studies and a quarter of a million children less than 2 years of age raised no substantial flags concerning the safety of early exposure to APAP

10.1515/med-2021-0302 83 LiS.LuoC.ChenS.ZhuangY.JiY.ZengY.et al (2023)